Description
Rabbit Monoclonal, RTU. Intended for in vitro diagnostic (IVD) use. This caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferative and differentiation of intestinal epithelial. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX-2 and carbonic anhydrase 1, a gene regulated by CDX-2, is reduced or absent. CDX-2 is one of the most important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract. References 1. Drummond F, etal. Ann Hum Genet 61(5): 393-400 2. Gregory PA, et al. Pharmacogenet Genomics 16(7): 527-36, 2006
Storage
Refrigerated Storage
Store refrigerated at 2°C to 8°C (36°F to 46°F)
Refrigerated storage upon delivery is important for correct product functionality.
