Mouse Monoclonal. Ready-to-Use. Intended for in vitro diagnostic (IVD) use. Anti-CD20 (B-cell Pan) reacts with a membrane antigen that is present in B-cells. This antibody recognizes Reed-Sternberg cells, predominant in Hodgkin’s disease, in a minority of cases. Since no staining of histiocytes or plasma cells has been observed and CD20 has not been detected in T-cell malignancies, it is a very strong marker of B-cell lymphomas. Anti-CD20 does not cross-react with non-hematopoietic neoplasms. References 1. Ishii, Y, et al., Clin Exp Immuno 1984;58:183-192 2. Davey, FR, et al., Am J Pathol 1987;129:54-63 3. Mason, DY, Am J Pathol. 1987;128:1-4 4. Browne P et al. Am J Clin Pathol. 2003 Nov;120(5): 767-777 5. Tzankov A et al. Clin Cancer Res. 2003 Apr;9(4): 1381-6